Intake of Calanus finmarchicus oil for 12 weeks improves omega-3 index in healthy older subjects engaging in an exercise programme
The n-3 PUFA, EPA and DHA, play an important role in human health. As the intake of EPA and DHA from the diet is often inadequate, supplementation of those fatty acids is recommended. A novel source of n-3 PUFA is Calanus finmarchicus oil (CO) which contains fatty acids mainly bound in wax esters. T...
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| Veröffentlicht in: | British journal of nutrition 2021-02, Vol.125 (4), p.432-439 |
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| creator | Wasserfurth, Paulina Nebl, Josefine Boßlau, Tim Konstantin Krüger, Karsten Hahn, Andreas Schuchardt, Jan Philipp |
| description | The n-3 PUFA, EPA and DHA, play an important role in human health. As the intake of EPA and DHA from the diet is often inadequate, supplementation of those fatty acids is recommended. A novel source of n-3 PUFA is Calanus finmarchicus oil (CO) which contains fatty acids mainly bound in wax esters. To date, no data are available on the effects of long-term intake of this marine oil on n-3 PUFA blood levels. Therefore, the aim of this study was to evaluate the effect of CO on the n-3 PUFA blood levels using the omega-3 index (O3I). The data originate from a larger randomised controlled trial. For this analysis, samples from seventy-two participants (59·2 (sd 6·2) years, BMI 27·7 (sd 5·28) kg/m2) were analysed. Of those, thirty-six performed 2×/week exercise and received 2 g of CO, which provided 124 mg stearidonic acid (SDA), 109 mg EPA and 87 mg DHA daily (EXCO group), while the other group performed exercise only (EX group) and served as a control for this analysis. The O3I increased from 6·07 (sd 1·29) % at baseline to 7·37 (sd 1·10) % after 12 weeks within the EXCO group (P < 0·001), while there were no significant changes in the EX group (6·01 (sd 1·26)–6·15 (sd 1·32) %, P = 0·238). These data provide first evidence that wax ester-bound n-3 PUFA from CO can significantly increase the O3I despite relatively low EPA + DHA amounts. Further, the effects of exercise could be excluded. |
| doi_str_mv | 10.1017/S0007114520002809 |
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As the intake of EPA and DHA from the diet is often inadequate, supplementation of those fatty acids is recommended. A novel source of n-3 PUFA is Calanus finmarchicus oil (CO) which contains fatty acids mainly bound in wax esters. To date, no data are available on the effects of long-term intake of this marine oil on n-3 PUFA blood levels. Therefore, the aim of this study was to evaluate the effect of CO on the n-3 PUFA blood levels using the omega-3 index (O3I). The data originate from a larger randomised controlled trial. For this analysis, samples from seventy-two participants (59·2 (sd 6·2) years, BMI 27·7 (sd 5·28) kg/m2) were analysed. Of those, thirty-six performed 2×/week exercise and received 2 g of CO, which provided 124 mg stearidonic acid (SDA), 109 mg EPA and 87 mg DHA daily (EXCO group), while the other group performed exercise only (EX group) and served as a control for this analysis. The O3I increased from 6·07 (sd 1·29) % at baseline to 7·37 (sd 1·10) % after 12 weeks within the EXCO group (P < 0·001), while there were no significant changes in the EX group (6·01 (sd 1·26)–6·15 (sd 1·32) %, P = 0·238). These data provide first evidence that wax ester-bound n-3 PUFA from CO can significantly increase the O3I despite relatively low EPA + DHA amounts. Further, the effects of exercise could be excluded.</description><identifier>ISSN: 0007-1145</identifier><identifier>EISSN: 1475-2662</identifier><identifier>DOI: 10.1017/S0007114520002809</identifier><identifier>PMID: 32698912</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Angina pectoris ; Blood ; Blood levels ; Calanus finmarchicus ; Carbon monoxide ; Cholesterol ; Diet ; Dietary supplements ; Esters ; Exercise ; Fatty acids ; Fish oils ; Fitness training programs ; Human and Clinical Nutrition ; Indexing ; Laboratories ; Nutrition research ; Oil ; Oils & fats ; Participation ; Polyunsaturated fatty acids ; Questionnaires ; Waxes</subject><ispartof>British journal of nutrition, 2021-02, Vol.125 (4), p.432-439</ispartof><rights>The Author(s), 2020. Published by Cambridge University Press on behalf of The Nutrition Society</rights><rights>The Author(s), 2020. 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As the intake of EPA and DHA from the diet is often inadequate, supplementation of those fatty acids is recommended. A novel source of n-3 PUFA is Calanus finmarchicus oil (CO) which contains fatty acids mainly bound in wax esters. To date, no data are available on the effects of long-term intake of this marine oil on n-3 PUFA blood levels. Therefore, the aim of this study was to evaluate the effect of CO on the n-3 PUFA blood levels using the omega-3 index (O3I). The data originate from a larger randomised controlled trial. For this analysis, samples from seventy-two participants (59·2 (sd 6·2) years, BMI 27·7 (sd 5·28) kg/m2) were analysed. Of those, thirty-six performed 2×/week exercise and received 2 g of CO, which provided 124 mg stearidonic acid (SDA), 109 mg EPA and 87 mg DHA daily (EXCO group), while the other group performed exercise only (EX group) and served as a control for this analysis. 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Further, the effects of exercise could be excluded.</description><subject>Angina pectoris</subject><subject>Blood</subject><subject>Blood levels</subject><subject>Calanus finmarchicus</subject><subject>Carbon monoxide</subject><subject>Cholesterol</subject><subject>Diet</subject><subject>Dietary supplements</subject><subject>Esters</subject><subject>Exercise</subject><subject>Fatty acids</subject><subject>Fish oils</subject><subject>Fitness training programs</subject><subject>Human and Clinical Nutrition</subject><subject>Indexing</subject><subject>Laboratories</subject><subject>Nutrition research</subject><subject>Oil</subject><subject>Oils & fats</subject><subject>Participation</subject><subject>Polyunsaturated fatty acids</subject><subject>Questionnaires</subject><subject>Waxes</subject><issn>0007-1145</issn><issn>1475-2662</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>IKXGN</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kU1v1DAQhi0EoqXwA7ggS1y4BOxxEjsXJLTio1IlDsA5mjiTrLeJvdhJaa_8crzqUr7Exfbofea1Xw9jT6V4KYXUrz4JIbSUZQX5AEY099ipLHVVQF3DfXZ6kIuDfsIepbTLpZGiechOFNSNaSScsu_nfsFL4mHgG5zQr4kPzs8Y7dbZXAQ38SFELoF_I7pM3M37GK4oKzONWCjufE_XeeVbwmnZ3vAw9RR5Wrsd2SVx8iOOzo8HBD2na4rWJeLZZow4z_SYPRhwSvTkuJ-xL-_eft58KC4-vj_fvLkobAlmKRohSgWEaEAqMCQ7YxWi0AgKmgoqtMOgQVKvmg5NTdCUfVUKgY2SQ9-pM_b61ne_djP1lvwScWr30eW4N21A1_6peLdtx3DValOWtaizwYujQQxfV0pLO7tkacrfRmFNLZRQV0qrqsro87_QXVijz_EypY0GLSqVKXlL2RhSijTcPUaK9jDh9p8J555nv6e46_g50gyooynOXXT9SL_u_r_tD3kzsSw</recordid><startdate>20210228</startdate><enddate>20210228</enddate><creator>Wasserfurth, Paulina</creator><creator>Nebl, Josefine</creator><creator>Boßlau, Tim Konstantin</creator><creator>Krüger, Karsten</creator><creator>Hahn, Andreas</creator><creator>Schuchardt, Jan Philipp</creator><general>Cambridge University Press</general><scope>IKXGN</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7T5</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20210228</creationdate><title>Intake of Calanus finmarchicus oil for 12 weeks improves omega-3 index in healthy older subjects engaging in an exercise programme</title><author>Wasserfurth, Paulina ; 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As the intake of EPA and DHA from the diet is often inadequate, supplementation of those fatty acids is recommended. A novel source of n-3 PUFA is Calanus finmarchicus oil (CO) which contains fatty acids mainly bound in wax esters. To date, no data are available on the effects of long-term intake of this marine oil on n-3 PUFA blood levels. Therefore, the aim of this study was to evaluate the effect of CO on the n-3 PUFA blood levels using the omega-3 index (O3I). The data originate from a larger randomised controlled trial. For this analysis, samples from seventy-two participants (59·2 (sd 6·2) years, BMI 27·7 (sd 5·28) kg/m2) were analysed. Of those, thirty-six performed 2×/week exercise and received 2 g of CO, which provided 124 mg stearidonic acid (SDA), 109 mg EPA and 87 mg DHA daily (EXCO group), while the other group performed exercise only (EX group) and served as a control for this analysis. The O3I increased from 6·07 (sd 1·29) % at baseline to 7·37 (sd 1·10) % after 12 weeks within the EXCO group (P < 0·001), while there were no significant changes in the EX group (6·01 (sd 1·26)–6·15 (sd 1·32) %, P = 0·238). These data provide first evidence that wax ester-bound n-3 PUFA from CO can significantly increase the O3I despite relatively low EPA + DHA amounts. Further, the effects of exercise could be excluded.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>32698912</pmid><doi>10.1017/S0007114520002809</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Angina pectoris Blood Blood levels Calanus finmarchicus Carbon monoxide Cholesterol Diet Dietary supplements Esters Exercise Fatty acids Fish oils Fitness training programs Human and Clinical Nutrition Indexing Laboratories Nutrition research Oil Oils & fats Participation Polyunsaturated fatty acids Questionnaires Waxes |
| title | Intake of Calanus finmarchicus oil for 12 weeks improves omega-3 index in healthy older subjects engaging in an exercise programme |
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