Can SARS-CoV-2 infect the central nervous system via the olfactory bulb or the blood-brain barrier?

•SARS-CoV-2 may infect immature olfactory sensory neurons.•Olfactory sensory neurons and the blood brain barrier may allow infection of the brain.•The distribution of ACE2, or novel cellular entry proteins, will limit viral spread.•Animal models may be of limited value in studying COVID-19 and the b...

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2021-07, Vol.95, p.7-14
Hauptverfasser:	Burks, Susan M., Rosas-Hernandez, Hector, Alejandro Ramirez-Lee, Manuel, Cuevas, Elvis, Talpos, John C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood-Brain Barrier Central Nervous System China COVID-19 Humans Olfactory Bulb Review SARS-CoV-2
Online-Zugang:	Volltext
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