Enlargement of Intrathoracic Goiter with Unilateral Phrenic Nerve Paralysis Leading to Cardiopulmonary Arrest
As an intrathoracic goiter expands, it causes airway stenosis and phrenic nerve paralysis, and slight respiratory stimuli can trigger sudden life-threatening hypoventilation. A 78-year-old obese woman with a large intrathoracic goiter was found unconscious with agonal breathing in her room early in...
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| Veröffentlicht in: | Internal Medicine 2021/01/01, Vol.60(1), pp.91-97 |
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| container_title | Internal Medicine |
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| creator | Shioya, Nobuki Inoue, Nozomu Kawashima, Naonori Tsukamoto, Yuki Nakayama, Miyabi Hazama, Koji Shichinohe, Yasuo Suzuki, Fumiyuki Honma, Naotake |
| description | As an intrathoracic goiter expands, it causes airway stenosis and phrenic nerve paralysis, and slight respiratory stimuli can trigger sudden life-threatening hypoventilation. A 78-year-old obese woman with a large intrathoracic goiter was found unconscious with agonal breathing in her room early in the morning. Cardiopulmonary resuscitation restored spontaneous circulation. She underwent surgical removal of the goiter; however, she required long-term mechanical ventilation because of atelectasis due to phrenic nerve paralysis. In patients with large intrathoracic goiters, difficulty breathing on exertion and diaphragm elevation on chest X-ray may be significant findings predicting future respiratory failure. |
| doi_str_mv | 10.2169/internalmedicine.5075-20 |
| format | Article |
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A 78-year-old obese woman with a large intrathoracic goiter was found unconscious with agonal breathing in her room early in the morning. Cardiopulmonary resuscitation restored spontaneous circulation. She underwent surgical removal of the goiter; however, she required long-term mechanical ventilation because of atelectasis due to phrenic nerve paralysis. 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Med.</addtitle><description>As an intrathoracic goiter expands, it causes airway stenosis and phrenic nerve paralysis, and slight respiratory stimuli can trigger sudden life-threatening hypoventilation. A 78-year-old obese woman with a large intrathoracic goiter was found unconscious with agonal breathing in her room early in the morning. Cardiopulmonary resuscitation restored spontaneous circulation. She underwent surgical removal of the goiter; however, she required long-term mechanical ventilation because of atelectasis due to phrenic nerve paralysis. In patients with large intrathoracic goiters, difficulty breathing on exertion and diaphragm elevation on chest X-ray may be significant findings predicting future respiratory failure.</description><subject>Aged</subject><subject>Atelectasis</subject><subject>cardiopulmonary arrest</subject><subject>Case Report</subject><subject>Diaphragm</subject><subject>Female</subject><subject>Goiter</subject><subject>Goiter, Substernal - complications</subject><subject>Goiter, Substernal - diagnostic imaging</subject><subject>Goiter, Substernal - surgery</subject><subject>Heart Arrest - etiology</subject><subject>Humans</subject><subject>Hypoventilation</subject><subject>Internal medicine</subject><subject>intrathoracic goiter</subject><subject>Mechanical ventilation</subject><subject>Paralysis</subject><subject>Phrenic Nerve</subject><subject>phrenic nerve paralysis</subject><subject>Respiration</subject><subject>Stenosis</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkU1vGyEQhlHVqnHS_oUKqZdeNuVjYXcvlSIrTSJZaQ7NGY1Z1sZiwQU2Uf59Wdm12vQyI5iHd2Z4EcKUXDIqu6_WZxM9uNH0VltvLgVpRMXIG7SgvO6qhnHxFi1IR9uKlXCGzlPaEcLbpmPv0RlnbccZ6xZovPYO4saMxmccBnznc4S8DRG01fgm2NIIP9u8xY_eOigncPhhG40v5XsTnwx-gHL3kmzCKwO99RucA15C7G3YT24MHuILvorRpPwBvRvAJfPxmC_Q4_frn8vbavXj5m55taq0JF2uekaHZi0aQoBLLlsQnNfQ1u2acEGJ7Mr0renWUrSsH_qe1hJg4E1PBy00pfwCfTvo7qd1-SNt5q2c2kc7lmFUAKv-rXi7VZvwpJqWi7ppisCXo0AMv6YyuRpt0sY58CZMSbG6JlIKUpOCfn6F7sI0mzNTTS2kKKlQ7YHSMaQUzXAahhI1e6pee6pmTxWbG3z6e5nTwz8mFuD-AOxSho05ARCz1c78ryyJonM4djiBegtRGc9_A3kEwZQ</recordid><startdate>20210101</startdate><enddate>20210101</enddate><creator>Shioya, Nobuki</creator><creator>Inoue, Nozomu</creator><creator>Kawashima, Naonori</creator><creator>Tsukamoto, Yuki</creator><creator>Nakayama, Miyabi</creator><creator>Hazama, Koji</creator><creator>Shichinohe, Yasuo</creator><creator>Suzuki, Fumiyuki</creator><creator>Honma, Naotake</creator><general>The Japanese Society of Internal Medicine</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20210101</creationdate><title>Enlargement of Intrathoracic Goiter with Unilateral Phrenic Nerve Paralysis Leading to Cardiopulmonary Arrest</title><author>Shioya, Nobuki ; Inoue, Nozomu ; Kawashima, Naonori ; Tsukamoto, Yuki ; Nakayama, Miyabi ; Hazama, Koji ; Shichinohe, Yasuo ; Suzuki, Fumiyuki ; Honma, Naotake</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c609t-d21f7b5700a36368a5334a848b03510698938e9b6582dfdd146aaf37d1fc5c113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Aged</topic><topic>Atelectasis</topic><topic>cardiopulmonary arrest</topic><topic>Case Report</topic><topic>Diaphragm</topic><topic>Female</topic><topic>Goiter</topic><topic>Goiter, Substernal - complications</topic><topic>Goiter, Substernal - diagnostic imaging</topic><topic>Goiter, Substernal - surgery</topic><topic>Heart Arrest - etiology</topic><topic>Humans</topic><topic>Hypoventilation</topic><topic>Internal medicine</topic><topic>intrathoracic goiter</topic><topic>Mechanical ventilation</topic><topic>Paralysis</topic><topic>Phrenic Nerve</topic><topic>phrenic nerve paralysis</topic><topic>Respiration</topic><topic>Stenosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shioya, Nobuki</creatorcontrib><creatorcontrib>Inoue, Nozomu</creatorcontrib><creatorcontrib>Kawashima, Naonori</creatorcontrib><creatorcontrib>Tsukamoto, Yuki</creatorcontrib><creatorcontrib>Nakayama, Miyabi</creatorcontrib><creatorcontrib>Hazama, Koji</creatorcontrib><creatorcontrib>Shichinohe, Yasuo</creatorcontrib><creatorcontrib>Suzuki, Fumiyuki</creatorcontrib><creatorcontrib>Honma, Naotake</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shioya, Nobuki</au><au>Inoue, Nozomu</au><au>Kawashima, Naonori</au><au>Tsukamoto, Yuki</au><au>Nakayama, Miyabi</au><au>Hazama, Koji</au><au>Shichinohe, Yasuo</au><au>Suzuki, Fumiyuki</au><au>Honma, Naotake</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enlargement of Intrathoracic Goiter with Unilateral Phrenic Nerve Paralysis Leading to Cardiopulmonary Arrest</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. 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| subjects | Aged Atelectasis cardiopulmonary arrest Case Report Diaphragm Female Goiter Goiter, Substernal - complications Goiter, Substernal - diagnostic imaging Goiter, Substernal - surgery Heart Arrest - etiology Humans Hypoventilation Internal medicine intrathoracic goiter Mechanical ventilation Paralysis Phrenic Nerve phrenic nerve paralysis Respiration Stenosis |
| title | Enlargement of Intrathoracic Goiter with Unilateral Phrenic Nerve Paralysis Leading to Cardiopulmonary Arrest |
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