Phytoecdysteroids Do Not Have Anabolic Effects in Skeletal Muscle in Sedentary Aging Mice

Skeletal muscle mass and strength are lost with aging. Phytoecdysteroids, in particular 20-hydroxyecdysone (20E), increase protein synthesis in C2C12 skeletal muscle cells and muscle strength in young rats. The objective of this study was to determine whether an extract from (ATE), enriched in phyto...

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Veröffentlicht in:	International journal of environmental research and public health 2021-01, Vol.18 (2), p.370
Hauptverfasser:	Lawrence, Marcus M, Zwetsloot, Kevin A, Arthur, Susan T, Sherman, Chase A, Huot, Joshua R, Badmaev, Vladimir, Grace, Mary, Lila, Mary Ann, Nieman, David C, Shanely, R Andrew
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Aging AKT protein Anabolic Agents Animals Antibodies Enzymes Laboratory animals Male Mice Mice, Inbred C57BL mRNA Muscle strength Muscle, Skeletal Muscles Musculoskeletal system Myostatin Phosphatidylinositol 3-Kinases Protein biosynthesis Protein synthesis Proteins Rats Sarcopenia Sedentary behavior Signal transduction Skeletal muscle Young adults
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