Angiotensin-Converting Enzyme Inhibitors Reduce Uterine Fibroid Incidence in Hypertensive Women

Absctract Context In vitro and in vivo evidence has supported the role of angiotensin II blockade in reducing leiomyoma cell proliferation and growth. However, no population-based study to date has investigated this potential association. Objective This work aims to determine whether prior angiotens...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2021-02, Vol.106 (2), p.e650-e659
Hauptverfasser:	Fischer, Nicole M, Nieuwenhuis, Tim O, Singh, Bhuchitra, Yenokyan, Gayane, Segars, James H
Format:	Artikel
Sprache:	eng
Schlagworte:	ACE inhibitors Adolescent Adult Age Aged Angiotensin Angiotensin II Angiotensin-converting enzyme inhibitors Angiotensin-Converting Enzyme Inhibitors - therapeutic use Case-Control Studies Cell proliferation Clinical s Databases, Factual Diagnosis Enzymes Female Fibroids Health insurance industry Humans Hypertension Hypertension - drug therapy Hypertension - epidemiology Incidence Leiomyoma - epidemiology Middle Aged Online databases Peptidyl-dipeptidase A Population studies Retrospective Studies Risk Factors Telmisartan Ulipristal acetate United States - epidemiology Uterine Neoplasms - epidemiology Young Adult
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