Traveling Salesman Finds Random Walk: A Curve Reconstruction Algorithm for Supercoiled DNA

DNA supercoiling plays an important role in a variety of cellular processes, including transcription, replication, and DNA compaction. To fully understand these processes, we must uncover and characterize the dynamics of supercoiled DNA. However, supercoil dynamics are difficult to access because of...

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Veröffentlicht in:Biophysical journal 2020-12, Vol.119 (12), p.2517-2523
Hauptverfasser: Babamohammadi, Saeed, Lillian, Todd D.
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Sprache:eng
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