Multiple sclerosis iPS-derived oligodendroglia conserve their properties to functionally interact with axons and glia in vivo

Remyelination failure in multiple sclerosis (MS) is associated with a migration/differentiation block of oligodendroglia. The reason for this block is highly debated. It could result from disease-related extrinsic or intrinsic regulators in oligodendroglial biology. To avoid confounding immune-media...

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Veröffentlicht in:Science advances 2020-12, Vol.6 (49)
Hauptverfasser: Mozafari, Sabah, Starost, Laura, Manot-Saillet, Blandine, Garcia-Diaz, Beatriz, Xu, Yu Kang T, Roussel, Delphine, Levy, Marion J F, Ottoboni, Linda, Kim, Kee-Pyo, Schöler, Hans R, Kennedy, Timothy E, Antel, Jack P, Martino, Gianvito, Angulo, Maria Cecilia, Kuhlmann, Tanja, Baron-Van Evercooren, Anne
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