Association of Metformin Use With Age-Related Macular Degeneration: A Case-Control Study

IMPORTANCE: Age-related macular degeneration (AMD), the leading cause of irreversible blindness in older adults, appears to have no effective preventive measures. The common antidiabetic drug metformin has been shown to have protective outcomes in multiple age-associated diseases and may have the po...

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Veröffentlicht in:	Archives of ophthalmology (1960) 2021-03, Vol.139 (3), p.302-309
Hauptverfasser:	Blitzer, Andrea L, Ham, Sandra A, Colby, Kathryn A, Skondra, Dimitra
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aged Aged, 80 and over Antidiabetics Blindness Case-Control Studies Clinical trials Comments Diabetes Diabetes mellitus Diabetes Mellitus - drug therapy Diabetic retinopathy Dosage Drug dosages Female Humans Hypoglycemic Agents - adverse effects Hypoglycemic Agents - therapeutic use Incidence Macular degeneration Macular Degeneration - epidemiology Macular Degeneration - etiology Male Metformin Metformin - adverse effects Metformin - therapeutic use Middle Aged Online First Original Investigation Prospective Studies Retina - drug effects Retina - pathology Retinopathy Risk Assessment - methods Risk Factors United States - epidemiology Visual Acuity
Online-Zugang:	Volltext
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