The clinical relevance of the Hippo pathway in pancreatic ductal adenocarcinoma

Purpose The Hippo pathway has broadened in cancer research in the past decade and revealed itself to be an important driver for tumorigenesis and metastatic spread. In this study, we investigated the clinical relevance of the Hippo pathway with regard to metastatic invasion, patients’ outcome and hi...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2021-02, Vol.147 (2), p.373-391
Hauptverfasser:	Drexler, Richard, Küchler, Mirco, Wagner, Kim C., Reese, Tim, Feyerabend, Bernd, Kleine, Moritz, Oldhafer, Karl J.
Format:	Artikel
Sprache:	eng
Schlagworte:	14-3-3 protein Adenocarcinoma Aged Cancer Research Carcinoma, Pancreatic Ductal - metabolism Carcinoma, Pancreatic Ductal - mortality Carcinoma, Pancreatic Ductal - pathology Cell Cycle Proteins - genetics DNA-Binding Proteins - genetics Female Hematology Humans Immunohistochemistry Internal Medicine Male Medicine Medicine & Public Health Metastases Metastasis Neoplasm Metastasis Nuclear Proteins - genetics Oncology Original Article – Cancer Research Original – Cancer Research Pancreas Pancreatic cancer Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - mortality Pancreatic Neoplasms - pathology Paraffin Patients Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - physiology Signal Transduction - physiology Surgery Transcription factors Transcription Factors - genetics Tumorigenesis Tumors Yes-associated protein
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