Level of the SARS-CoV-2 receptor ACE2 activity is highly elevated in old-aged patients with aortic stenosis: implications for ACE2 as a biomarker for the severity of COVID-19

Coronavirus disease 2019 (COVID-19) has a high mortality in elderly patients with pre-existing cardiovascular diseases. The cellular receptor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the angiotensin-converting enzyme 2 (ACE2), thereby implicating a link between cardiovascul...

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Veröffentlicht in:	GeroScience 2021-02, Vol.43 (1), p.19-29
Hauptverfasser:	Fagyas, Miklós, Kertész, Attila, Siket, Ivetta Mányiné, Bánhegyi, Viktor, Kracskó, Bertalan, Szegedi, Andrea, Szokol, Miklós, Vajda, Gusztáv, Rácz, Ildikó, Gulyás, Hajnalka, Szkibák, Noémi, Rácz, Vivienn, Csanádi, Zoltán, Papp, Zoltán, Tóth, Attila, Sipka, Sándor
Format:	Artikel
Sprache:	eng
Schlagworte:	ACE2 Aged Angiotensin Angiotensin-Converting Enzyme 2 Aortic stenosis Aortic Valve Stenosis Biomarkers Biomedical and Life Sciences Blood pressure Cardiovascular diseases Cell Biology Coronaviruses COVID-19 Flow velocity Geriatrics/Gerontology Heart Humans Hypertension Inflammation Life Sciences Middle Aged Molecular Medicine Mortality Original Original Article Peptidyl-Dipeptidase A Renin-Angiotensin System SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Stenosis Stroke Volume Ventricle Ventricular Function, Left
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