Assessment of Copper Nanoclusters for Accurate in Vivo Tumor Imaging and Potential for Translation

Nanoparticles have been widely used for preclinical cancer imaging. However, their successful clinical translation is largely hampered by potential toxicity, unsatisfactory detection of malignancy at early stages, inaccurate diagnosis of tumor biomarkers, and histology for imaging-guided treatment....

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Veröffentlicht in:	ACS applied materials & interfaces 2019-06, Vol.11 (22), p.19669-19678
Hauptverfasser:	Heo, Gyu Seong, Zhao, Yongfeng, Sultan, Deborah, Zhang, Xiaohui, Detering, Lisa, Luehmann, Hannah P, Zhang, Xiangyu, Li, Richen, Choksi, Ankur, Sharp, Savannah, Levingston, Sidney, Primeau, Tina, Reichert, David E, Sun, Guorong, Razani, Babak, Li, Shunqiang, Weilbaecher, Katherine N, Dehdashti, Farrokh, Wooley, Karen L, Liu, Yongjian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast Neoplasms - diagnostic imaging Copper - adverse effects Copper - chemistry Copper Radioisotopes - chemistry Drug Carriers - chemistry Female Humans Mice Nanoparticles - adverse effects Nanoparticles - chemistry Peptides, Cyclic - chemistry Positron-Emission Tomography Receptors, CXCR4 - metabolism Triple Negative Breast Neoplasms - diagnostic imaging
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