Evodiamine inhibits both stem cell and non-stem-cell populations in human cancer cells by targeting heat shock protein 70

Cancer stem cells (CSCs) are known to cause tumor recurrence and drug resistance. The heat shock protein (HSP) system plays a major role in preserving expression and function of numerous oncoproteins, including those involved in the CSC activities. We explored novel anticancer drugs, especially thos...

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Veröffentlicht in:Theranostics 2021, Vol.11 (6), p.2932-2952
Hauptverfasser: Hyun, Seung Yeob, Le, Huong Thuy, Min, Hye-Young, Pei, Honglan, Lim, Yijae, Song, Injae, Nguyen, Yen T K, Hong, Suckchang, Han, Byung Woo, Lee, Ho-Young
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Sprache:eng
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