Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine

Terminally differentiated murine osteocytes and adipocytes can be reprogrammed using platelet-derived growth factor-AB and 5-azacytidine into multipotent stem cells with stromal cell characteristics. We have now optimized culture conditions to reprogram human adipocytes into induced multipotent stem...

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Veröffentlicht in:	Science advances 2021-01, Vol.7 (3)
Hauptverfasser:	Yeola, Avani, Subramanian, Shruthi, Oliver, Rema A, Lucas, Christine A, Thoms, Julie A I, Yan, Feng, Olivier, Jake, Chacon, Diego, Tursky, Melinda L, Srivastava, Pallavi, Potas, Jason R, Hung, Tzongtyng, Power, Carl, Hardy, Philip, Ma, David D, Kilian, Kristopher A, McCarroll, Joshua, Kavallaris, Maria, Hesson, Luke B, Beck, Dominik, Curtis, David J, Wong, Jason W H, Hardeman, Edna C, Walsh, William R, Mobbs, Ralph, Chandrakanthan, Vashe, Pimanda, John E
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Biology SciAdv r-articles
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