Role of GATA3 exon 6 germline mutations in breast cancer progression in Egyptian female patients

Several mutations act as driver mutations in breast cancer, including GATA3 mutations. Reports of the relation between GATA3 mutations and breast cancer prognosis remain conflicting. Also, the role of GATA3 germline mutations is not well studied. We hypothesize that different mutation types could ha...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2021-01, Vol.246 (1), p.40-47
Hauptverfasser:	Ibrahim, Iman H, Abdel-Aziz, Heba G, Hassan, Fatema EM, El-Sameea, Hesham SA
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Neoplasms - genetics Breast Neoplasms - pathology Codon - genetics Disease Progression DNA Mutational Analysis Egypt Exons - genetics Female GATA3 Transcription Factor - genetics Gene Expression Regulation, Neoplastic Germ-Line Mutation - genetics Humans Middle Aged Original Research
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