Long Noncoding RNA CCDC144NL-AS1 Promotes the Oncogenicity of Osteosarcoma by Acting as a Molecular Sponge for microRNA-490-3p and Thereby Increasing HMGA2 Expression

The long noncoding RNA CCDC144NL antisense RNA 1 (CCDC144NL-AS1) exhibits important functions in gastric cancer. In this study, we aimed to investigate the roles of CCDC144NL-AS1 in modulating the phenotype of osteosarcoma (OS) cells in vitro and in vivo and elucidate its underlying mechanisms. Reve...

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Veröffentlicht in:	OncoTargets and therapy 2021-01, Vol.14, p.1-13
Hauptverfasser:	He, Juliang, Guan, Jian, Liao, Shian, Wu, Zhenjie, Liu, Bin, Mo, Hao, Yuan, Zhenchao
Format:	Artikel
Sprache:	eng
Schlagworte:	Antisense RNA Apoptosis Bioinformatics Bone cancer Cell proliferation Flow cytometry Gastric cancer Gene expression Hospitals Immunoprecipitation Laboratory animals Medical prognosis Medical research MicroRNAs miRNA Original Research Osteosarcoma Phenotypes Plasmids Polymerase chain reaction Reverse transcription Sarcoma Signal transduction Western blotting Xenografts
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