Biological Aging Measures Based on Blood DNA Methylation and Risk of Cancer: A Prospective Study

Background We previously investigated the association between 5 “first-generation” measures of epigenetic aging and cancer risk in the Melbourne Collaborative Cohort Study. This study assessed cancer risk associations for 3 recently developed methylation-based biomarkers of aging: PhenoAge, GrimAge,...

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Veröffentlicht in:	JNCI cancer spectrum 2021-02, Vol.5 (1)
Hauptverfasser:	Dugué, Pierre-Antoine, Bassett, Julie K, Wong, Ee Ming, Joo, JiHoon E, Li, Shuai, Yu, Chenglong, Schmidt, Daniel F, Makalic, Enes, Doo, Nicole Wong, Buchanan, Daniel D, Hodge, Allison M, English, Dallas R, Hopper, John L, Giles, Graham G, Southey, Melissa C, Milne, Roger L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Aged Aging - blood Aging - genetics Biomarkers - blood Case-Control Studies Colorectal Neoplasms - blood Colorectal Neoplasms - genetics Confidence Intervals DNA - blood DNA Methylation Epigenesis, Genetic Female Humans Kidney Neoplasms - blood Kidney Neoplasms - genetics Logistic Models Lung Neoplasms - blood Lung Neoplasms - genetics Lymphoma, B-Cell - blood Lymphoma, B-Cell - genetics Male Middle Aged Neoplasms - blood Neoplasms - genetics Prospective Studies Prostatic Neoplasms - blood Prostatic Neoplasms - genetics Risk Factors Smoking Stomach Neoplasms - blood Stomach Neoplasms - genetics Telomere Telomere Homeostasis Urologic Neoplasms - blood Urologic Neoplasms - genetics
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