Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease

Little is known about the roles of myeloid cell subsets in kidney injury and in the limited ability of the organ to repair itself. Characterizing these cells based only on surface markers using flow cytometry might not provide a full phenotypic picture. Defining these cells at the single-cell, trans...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of the American Society of Nephrology 2020-12, Vol.31 (12), p.2833-2854
Hauptverfasser:	Conway, Bryan R, O'Sullivan, Eoin D, Cairns, Carolynn, O'Sullivan, James, Simpson, Daniel J, Salzano, Angela, Connor, Katie, Ding, Peng, Humphries, Duncan, Stewart, Kevin, Teenan, Oliver, Pius, Riinu, Henderson, Neil C, Bénézech, Cécile, Ramachandran, Prakash, Ferenbach, David, Hughes, Jeremy, Chandra, Tamir, Denby, Laura
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Basic Research Disease Models, Animal Disease Progression Kidney Diseases - etiology Kidney Diseases - metabolism Kidney Diseases - pathology Macrophages - physiology Male Mice Mice, Inbred C57BL Myeloid Cells - physiology Sequence Analysis, RNA Single-Cell Analysis Ureteral Obstruction - etiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!