Facile Synthesis and Metabolic Incorporation of m‑DAP Bioisosteres Into Cell Walls of Live Bacteria

Bacterial cell walls contain peptidoglycan (PG), a scaffold that provides proper rigidity to resist lysis from internal osmotic pressure and a barrier to protect cells against external stressors. It consists of repeating sugar units with a linkage to a stem peptide that becomes cross-linked by cell...

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Veröffentlicht in:	ACS chemical biology 2020-11, Vol.15 (11), p.2966-2975
Hauptverfasser:	Apostolos, Alexis J, Nelson, Julia M, Silva, José Rogério A, Lameira, Jerônimo, Achimovich, Alecia M, Gahlmann, Andreas, Alves, Cláudio N, Pires, Marcos M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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