In Situ Absorption Study of Acebutolol by Modulating P-glycoprotein with Verapamil in Rats

Acebutolol HCl (ABL) is a selective β-adrenergic receptor blocking agent that is preferably administered by the oral route despite its low bioavailability (30-50%). The purpose of this study was to evaluate the effect of verapamil HCl (VER) [as P-glycoprotein inhibitor (P-gp)] on the intestinal abso...

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Veröffentlicht in:Turkish journal of pharmaceutical sciences 2020-12, Vol.17 (6), p.673-678
Hauptverfasser: Abushammala, Issam Mohammed, Abuwaked, Elham Abed, Fayyad, Hanan Mohammed, Elqedra, Ahmed Fadel, Ramadan, Mai Abed Alrahman, Almasri, Ihab Mustafa
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Sprache:eng
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