Second heart sound splitting as an indicator of interventricular mechanical dyssynchrony using a novel splitting detection algorithm

Second heart sound (S2) splitting results from nonsimultaneous closures between aortic (A2) and pulmonic valves (P2) and may be used to detect timing differences (dyssynchrony) in relaxation between right (RV) and left ventricle (LV). However, overlap of A2 and P2 and the change in heart sound morph...

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