Mitotic cells can repair DNA double-strand breaks via a homology-directed pathway

Abstract The choice of repair pathways of DNA double-strand breaks (DSBs) is dependent upon the cell cycle phases. While homologous recombination repair (HRR) is active between the S and G2 phases, its involvement in mitotic DSB repair has not been examined in detail. In the present study, we develo...

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Veröffentlicht in:Journal of radiation research 2021-01, Vol.62 (1), p.25-33
Hauptverfasser: Sakamoto, Yuki, Kokuta, Tetsuya, Teshigahara, Ai, Iijima, Kenta, Kitao, Hiroyuki, Takata, Minoru, Tauchi, Hiroshi
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Sprache:eng
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