Selection of High-Affinity RNA Aptamers That Distinguish between Doxycycline and Tetracycline

Oligonucleotide aptamers are found in prokaryotes and eukaryotes, and they can be selected from large synthetic libraries to bind protein or small-molecule ligands with high affinities and specificities. Aptamers can function as biosensors, as protein recognition elements, and as components of ribos...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemistry (Easton) 2020-09, Vol.59 (37), p.3473-3486
Hauptverfasser:	Tickner, Zachary J, Zhong, Guocai, Sheptack, Kelly R, Farzan, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - metabolism Aptamers, Nucleotide - chemistry Aptamers, Nucleotide - isolation & purification Aptamers, Nucleotide - metabolism Binding Sites Doxycycline - chemistry Doxycycline - metabolism Gene Library Ligands RNA - chemistry SELEX Aptamer Technique - methods Tetracycline - chemistry Tetracycline - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!