Expression of MiR-608 in Nonsmall Cell Lung Cancer and Molecular Mechanism of Apoptosis and Migration of A549 Cells

Objective. This Work is aimed at exploring the effect of microRNA (MiR)-608 on the function of nonsmall cell lung cancer (NSCLC) A549 cells and related mechanisms. Methods. Blood samples of 106 NSCLC patients (experimental group) as well as 124 normal people (control group) were selected for relevan...

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Veröffentlicht in:	BioMed research international 2020, Vol.2020 (2020), p.1-8
Hauptverfasser:	Tian, Hui, Lu, Ming, Qi, Lei, Si, Libo, Gao, Cun, Li, Shuhai, Li, Lin, Yue, Weiming, Huang, Chu, Cheng, Chuanle
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Analysis Antineoplastic Agents - pharmacology Apoptosis Apoptosis - drug effects Apoptosis - genetics Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - metabolism Cell culture Cell migration Cell Movement - drug effects Cell Movement - genetics Deoxyribonucleic acid DNA DNA sequencing Doxorubicin Doxorubicin - pharmacology Gastric cancer Gene expression Gene Expression Regulation, Neoplastic - drug effects Gene Expression Regulation, Neoplastic - genetics Genetic aspects Genetic polymorphisms Genotyping Health aspects Humans Identification and classification Lung cancer Lung cancer, Non-small cell Lung Neoplasms - genetics Lung Neoplasms - metabolism Metastasis Methods MicroRNA MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA Morbidity Non-small cell lung carcinoma Nucleotide sequencing Patients Physiological aspects Polymerase chain reaction Polymorphism Properties Proteins Ribonucleic acid RNA Surgery Tissues Tumors Western blotting Western immunoblotting
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