Pivotal role of long non-coding ribonucleic acid-X-inactive specific transcript in regulating immune checkpoint programmed death ligand 1 through a shared pathway between miR-194-5p and miR-155-5p in hepatocellular carcinoma

Anti-programmed death therapy has thrust immunotherapy into the spotlight. However, such therapy has a modest response in hepatocellular carcinoma (HCC). Epigenetic immunomodulation is a suggestive combinatorial therapy with immune checkpoint blockade. Non-coding ribonucleic acid (ncRNA) driven regu...

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Veröffentlicht in:World journal of hepatology 2020-12, Vol.12 (12), p.1211-1227
Hauptverfasser: Atwa, Sara M, Handoussa, Heba, Hosny, Karim M, Odenthal, Margarete, El Tayebi, Hend M
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Sprache:eng
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