Chlorinated Guaiane-Type Sesquiterpene Lactones as Cytotoxic Agents against Human Tumor Cells

Guaiane-type sesquiterpene lactones are naturally occurring compounds which have attracted attention due to their array of biological activities. In this study, chlorinated guaianolides - , isolated from plants of the genus , were evaluated against the human leukemia cell lines HL-60, U-937, a speci...

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Veröffentlicht in:	International journal of molecular sciences 2020-12, Vol.21 (24), p.9767
Hauptverfasser:	Estévez-Sarmiento, Francisco, Saavedra, Ester, Ruiz-Estévez, Mercedes, León, Francisco, Quintana, José, Brouard, Ignacio, Estévez, Francisco
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Apoptosis Cytochromes c - metabolism Cytotoxins - pharmacology Humans Lactones - pharmacology Leukemia - drug therapy Leukemia - pathology Poly(ADP-ribose) Polymerases - metabolism Sesquiterpenes, Guaiane - chemistry U937 Cells
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