Improving Tumor-to-Background Contrast Through Hydrophilic Tetrazines: The Construction of 18F Labeled PET Agents Targeting Non-Small Cell Lung Carcinoma

Bioorthogonal reactions have been widely used in biomedical field. 18 F-TCO/Tetrazine ligation is the most reactive radiolabelled inverse electron demand Diels-Alder reactions, but its application had been limited due to modest contrast ratios of the resulting conjugates. Here we describe the use of...

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Veröffentlicht in:	Chemistry : a European journal 2020-03, Vol.26 (21), p.4690-4694
Hauptverfasser:	Feng, Huijuan, Zhang, He, Wang, Mengzhe, Vannam, Raghu, Wang, Hui, Yan, Xuefeng, Ouyang, Wei, Jia, Xinqiao, Fox, Joseph, Li, Zibo
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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