FOXM1/DVL2/Snail axis drives metastasis and chemoresistance of colorectal cancer

Colorectal cancer (CRC) is the third most common type of cancer worldwide. Metastasis and chemoresistance are regarded as the two leading causes of treatment failure and high mortality in CRC. Forkhead Box M1 (FOXM1) has been involved in malignant behaviors of cancer. However, the role and mechanism...

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Veröffentlicht in:	Aging (Albany, NY.) NY.), 2020-12, Vol.12 (23), p.24424-24440
Hauptverfasser:	Yang, Yuhan, Jiang, Hequn, Li, Wanxin, Chen, Linyi, Zhu, Wanglong, Xian, Yu, Han, Zhengyu, Yin, Lan, Liu, Yao, Wang, Yi, Pan, Kejian, Zhang, Kun
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology ATP Binding Cassette Transporter, Subfamily B - genetics ATP Binding Cassette Transporter, Subfamily B - metabolism Cell Line, Tumor Cell Movement - drug effects Colorectal Neoplasms - drug therapy Colorectal Neoplasms - genetics Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Dishevelled Proteins - genetics Dishevelled Proteins - metabolism Drug Resistance, Neoplasm - genetics Epithelial-Mesenchymal Transition - drug effects Forkhead Box Protein M1 - genetics Forkhead Box Protein M1 - metabolism Gene Expression Regulation, Neoplastic Humans Neoplasm Metastasis Oxaliplatin - pharmacology Research Paper Snail Family Transcription Factors - genetics Snail Family Transcription Factors - metabolism Vincristine - pharmacology Wnt Signaling Pathway
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