The human tumor microbiome is composed of tumor type-specific intracellular bacteria

Bacteria were first detected in human tumors more than 100 years ago, but the characterization of the tumor microbiome has remained challenging because of its low biomass. We undertook a comprehensive analysis of the tumor microbiome, studying 1526 tumors and their adjacent normal tissues across sev...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 2020-05, Vol.368 (6494), p.973-980
Hauptverfasser:	Nejman, Deborah, Livyatan, Ilana, Fuks, Garold, Gavert, Nancy, Zwang, Yaara, Geller, Leore T, Rotter-Maskowitz, Aviva, Weiser, Roi, Mallel, Giuseppe, Gigi, Elinor, Meltser, Arnon, Douglas, Gavin M, Kamer, Iris, Gopalakrishnan, Vancheswaran, Dadosh, Tali, Levin-Zaidman, Smadar, Avnet, Sofia, Atlan, Tehila, Cooper, Zachary A, Arora, Reetakshi, Cogdill, Alexandria P, Khan, Md Abdul Wadud, Ologun, Gabriel, Bussi, Yuval, Weinberger, Adina, Lotan-Pompan, Maya, Golani, Ofra, Perry, Gili, Rokah, Merav, Bahar-Shany, Keren, Rozeman, Elisa A, Blank, Christian U, Ronai, Anat, Shaoul, Ron, Amit, Amnon, Dorfman, Tatiana, Kremer, Ran, Cohen, Zvi R, Harnof, Sagi, Siegal, Tali, Yehuda-Shnaidman, Einav, Gal-Yam, Einav Nili, Shapira, Hagit, Baldini, Nicola, Langille, Morgan G I, Ben-Nun, Alon, Kaufman, Bella, Nissan, Aviram, Golan, Talia, Dadiani, Maya, Levanon, Keren, Bar, Jair, Yust-Katz, Shlomit, Barshack, Iris, Peeper, Daniel S, Raz, Dan J, Segal, Eran, Wargo, Jennifer A, Sandbank, Judith, Shental, Noam, Straussman, Ravid
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria - classification Bacteria - genetics Bacteria - isolation & purification Breast - microbiology Colon - microbiology Female Humans Immunotherapy Lung - microbiology Macrophages - microbiology Male Microbiota Neoplasms - microbiology Neoplasms - therapy Ovary - microbiology RNA, Ribosomal, 16S - genetics
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