Pseudomonas laryngeal perichondritis: unexpected diagnosis
A 57-year-old male chronic smoker with underlying diabetes mellitus presented with dysphonia associated with cough, dysphagia and reduced effort tolerance of 3 months’ duration. Videoendoscope finding revealed bilateral polypoidal and erythematous true and false vocal fold with small glottic airway....
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| Veröffentlicht in: | BMJ case reports 2020-12, Vol.13 (12), p.e237129 |
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| creator | Zainal Abidin, Siti Salwa Kew, Thean Yean Azman, Mawaddah Mat Baki, Marina |
| description | A 57-year-old male chronic smoker with underlying diabetes mellitus presented with dysphonia associated with cough, dysphagia and reduced effort tolerance of 3 months’ duration. Videoendoscope finding revealed bilateral polypoidal and erythematous true and false vocal fold with small glottic airway. The patient was initially treated as having tuberculous laryngitis and started on antituberculous drug. However, no improvement was observed. CT of the neck showed erosion of thyroid cartilage, which points to laryngeal carcinoma as a differential diagnosis. However, the erosion was more diffuse and appeared systemic in origin. The diagnosis of laryngeal perichondritis was made when the histopathological examination revealed features of inflammation, and the tracheal aspirate isolated Pseudomonas aeruginosa. The patient made a good recovery following treatment with oral ciprofloxacin. |
| doi_str_mv | 10.1136/bcr-2020-237129 |
| format | Article |
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Videoendoscope finding revealed bilateral polypoidal and erythematous true and false vocal fold with small glottic airway. The patient was initially treated as having tuberculous laryngitis and started on antituberculous drug. However, no improvement was observed. CT of the neck showed erosion of thyroid cartilage, which points to laryngeal carcinoma as a differential diagnosis. However, the erosion was more diffuse and appeared systemic in origin. The diagnosis of laryngeal perichondritis was made when the histopathological examination revealed features of inflammation, and the tracheal aspirate isolated Pseudomonas aeruginosa. The patient made a good recovery following treatment with oral ciprofloxacin.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2020-237129</identifier><identifier>PMID: 33370978</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd</publisher><subject>Abscesses ; Anti-Bacterial Agents - therapeutic use ; Antibiotics ; Cartilage ; Case Report ; Case reports ; Ciprofloxacin - therapeutic use ; Cough - microbiology ; Deglutition Disorders - microbiology ; Diabetes ; Diagnosis, Differential ; Dysphagia ; Dysphonia - microbiology ; ear ; Ears & hearing ; Edema ; Endoscopy ; Histopathology ; Humans ; Infections ; Inflammation ; Laryngeal Diseases - complications ; Laryngeal Diseases - diagnosis ; Laryngeal Diseases - drug therapy ; Laryngeal Diseases - microbiology ; Laryngeal Neoplasms - diagnosis ; Laryngoscopy ; Larynx ; Male ; Medical diagnosis ; Middle Aged ; nose and throat/otolaryngology ; otolaryngology / ENT ; Pseudomonas aeruginosa - isolation & purification ; Pseudomonas Infections - complications ; Pseudomonas Infections - diagnosis ; Pseudomonas Infections - drug therapy ; Pseudomonas Infections - microbiology ; Soil erosion ; Thyroid Cartilage - diagnostic imaging ; Thyroid Cartilage - microbiology ; Thyroid gland ; Tomography, X-Ray Computed ; Treatment Outcome ; Tuberculosis ; Tuberculosis, Laryngeal - diagnosis ; Vocal Cords - diagnostic imaging ; Vocal Cords - microbiology</subject><ispartof>BMJ case reports, 2020-12, Vol.13 (12), p.e237129</ispartof><rights>BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2020 BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. 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Videoendoscope finding revealed bilateral polypoidal and erythematous true and false vocal fold with small glottic airway. The patient was initially treated as having tuberculous laryngitis and started on antituberculous drug. However, no improvement was observed. CT of the neck showed erosion of thyroid cartilage, which points to laryngeal carcinoma as a differential diagnosis. However, the erosion was more diffuse and appeared systemic in origin. The diagnosis of laryngeal perichondritis was made when the histopathological examination revealed features of inflammation, and the tracheal aspirate isolated Pseudomonas aeruginosa. The patient made a good recovery following treatment with oral ciprofloxacin.</description><subject>Abscesses</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotics</subject><subject>Cartilage</subject><subject>Case Report</subject><subject>Case reports</subject><subject>Ciprofloxacin - therapeutic use</subject><subject>Cough - microbiology</subject><subject>Deglutition Disorders - microbiology</subject><subject>Diabetes</subject><subject>Diagnosis, Differential</subject><subject>Dysphagia</subject><subject>Dysphonia - microbiology</subject><subject>ear</subject><subject>Ears & hearing</subject><subject>Edema</subject><subject>Endoscopy</subject><subject>Histopathology</subject><subject>Humans</subject><subject>Infections</subject><subject>Inflammation</subject><subject>Laryngeal Diseases - complications</subject><subject>Laryngeal Diseases - diagnosis</subject><subject>Laryngeal Diseases - drug therapy</subject><subject>Laryngeal Diseases - microbiology</subject><subject>Laryngeal Neoplasms - diagnosis</subject><subject>Laryngoscopy</subject><subject>Larynx</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>Middle Aged</subject><subject>nose and throat/otolaryngology</subject><subject>otolaryngology / ENT</subject><subject>Pseudomonas aeruginosa - isolation & purification</subject><subject>Pseudomonas Infections - complications</subject><subject>Pseudomonas Infections - diagnosis</subject><subject>Pseudomonas Infections - drug therapy</subject><subject>Pseudomonas Infections - microbiology</subject><subject>Soil erosion</subject><subject>Thyroid Cartilage - diagnostic imaging</subject><subject>Thyroid Cartilage - microbiology</subject><subject>Thyroid gland</subject><subject>Tomography, X-Ray Computed</subject><subject>Treatment Outcome</subject><subject>Tuberculosis</subject><subject>Tuberculosis, Laryngeal - diagnosis</subject><subject>Vocal Cords - diagnostic imaging</subject><subject>Vocal Cords - microbiology</subject><issn>1757-790X</issn><issn>1757-790X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkc1LxDAQxYMoKurZmyx4EaWaNGmz8SDI4hcIelDwFiZNumZpkzVpRf97s66uHyCYywTmN4838xDaJviQEFoeqSpkOc5xllNOcrGE1gkveMYFflj-9l9DWzFOcHqUsCGjq2iNUsqx4MN1dHwbTa996x3EQQPh1Y0NNIOpCbZ69E4H29l4POideZmaqjN6oC2MnY82bqKVGppotj7qBro_P7sbXWbXNxdXo9PrTDGRd1lJKRhqihoPoQSuRI3LgpY5EMZ0ZbjBGIRmkKsCgGulWI01cBCgVV0VlG6gk7nutFetSSOuC9DIabBt8is9WPmz4-yjHPtnydMF2LvA3odA8E-9iZ1sbaxM04Azvo8yZ5xyhoeiTOjuL3Ti--DSejOKCE4xY4k6mlNV8DEGUy_MECxn0cgUjZxFI-fRpImd7zss-M8gErA_B1Q7-YfawRe8MPgX_QZ866Yb</recordid><startdate>20201222</startdate><enddate>20201222</enddate><creator>Zainal Abidin, Siti Salwa</creator><creator>Kew, Thean Yean</creator><creator>Azman, Mawaddah</creator><creator>Mat Baki, Marina</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-9282-874X</orcidid></search><sort><creationdate>20201222</creationdate><title>Pseudomonas laryngeal perichondritis: unexpected diagnosis</title><author>Zainal Abidin, Siti Salwa ; Kew, Thean Yean ; Azman, Mawaddah ; Mat Baki, Marina</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b492t-633ae3e5f08a6a7b9f065362a144dce7e00a9d4a2b5aa7dbb4f0da7a9adbfc533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Abscesses</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antibiotics</topic><topic>Cartilage</topic><topic>Case Report</topic><topic>Case reports</topic><topic>Ciprofloxacin - therapeutic use</topic><topic>Cough - microbiology</topic><topic>Deglutition Disorders - microbiology</topic><topic>Diabetes</topic><topic>Diagnosis, Differential</topic><topic>Dysphagia</topic><topic>Dysphonia - microbiology</topic><topic>ear</topic><topic>Ears & hearing</topic><topic>Edema</topic><topic>Endoscopy</topic><topic>Histopathology</topic><topic>Humans</topic><topic>Infections</topic><topic>Inflammation</topic><topic>Laryngeal Diseases - complications</topic><topic>Laryngeal Diseases - diagnosis</topic><topic>Laryngeal Diseases - drug therapy</topic><topic>Laryngeal Diseases - microbiology</topic><topic>Laryngeal Neoplasms - diagnosis</topic><topic>Laryngoscopy</topic><topic>Larynx</topic><topic>Male</topic><topic>Medical diagnosis</topic><topic>Middle Aged</topic><topic>nose and throat/otolaryngology</topic><topic>otolaryngology / ENT</topic><topic>Pseudomonas aeruginosa - isolation & purification</topic><topic>Pseudomonas Infections - complications</topic><topic>Pseudomonas Infections - diagnosis</topic><topic>Pseudomonas Infections - drug therapy</topic><topic>Pseudomonas Infections - microbiology</topic><topic>Soil erosion</topic><topic>Thyroid Cartilage - diagnostic imaging</topic><topic>Thyroid Cartilage - microbiology</topic><topic>Thyroid gland</topic><topic>Tomography, X-Ray Computed</topic><topic>Treatment Outcome</topic><topic>Tuberculosis</topic><topic>Tuberculosis, Laryngeal - diagnosis</topic><topic>Vocal Cords - diagnostic imaging</topic><topic>Vocal Cords - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zainal Abidin, Siti Salwa</creatorcontrib><creatorcontrib>Kew, Thean Yean</creatorcontrib><creatorcontrib>Azman, Mawaddah</creatorcontrib><creatorcontrib>Mat Baki, Marina</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zainal Abidin, Siti Salwa</au><au>Kew, Thean Yean</au><au>Azman, Mawaddah</au><au>Mat Baki, Marina</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pseudomonas laryngeal perichondritis: unexpected diagnosis</atitle><jtitle>BMJ case reports</jtitle><stitle>BMJ Case Rep</stitle><addtitle>BMJ Case Rep</addtitle><date>2020-12-22</date><risdate>2020</risdate><volume>13</volume><issue>12</issue><spage>e237129</spage><pages>e237129-</pages><issn>1757-790X</issn><eissn>1757-790X</eissn><abstract>A 57-year-old male chronic smoker with underlying diabetes mellitus presented with dysphonia associated with cough, dysphagia and reduced effort tolerance of 3 months’ duration. Videoendoscope finding revealed bilateral polypoidal and erythematous true and false vocal fold with small glottic airway. The patient was initially treated as having tuberculous laryngitis and started on antituberculous drug. However, no improvement was observed. CT of the neck showed erosion of thyroid cartilage, which points to laryngeal carcinoma as a differential diagnosis. However, the erosion was more diffuse and appeared systemic in origin. The diagnosis of laryngeal perichondritis was made when the histopathological examination revealed features of inflammation, and the tracheal aspirate isolated Pseudomonas aeruginosa. The patient made a good recovery following treatment with oral ciprofloxacin.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd</pub><pmid>33370978</pmid><doi>10.1136/bcr-2020-237129</doi><orcidid>https://orcid.org/0000-0002-9282-874X</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Abscesses Anti-Bacterial Agents - therapeutic use Antibiotics Cartilage Case Report Case reports Ciprofloxacin - therapeutic use Cough - microbiology Deglutition Disorders - microbiology Diabetes Diagnosis, Differential Dysphagia Dysphonia - microbiology ear Ears & hearing Edema Endoscopy Histopathology Humans Infections Inflammation Laryngeal Diseases - complications Laryngeal Diseases - diagnosis Laryngeal Diseases - drug therapy Laryngeal Diseases - microbiology Laryngeal Neoplasms - diagnosis Laryngoscopy Larynx Male Medical diagnosis Middle Aged nose and throat/otolaryngology otolaryngology / ENT Pseudomonas aeruginosa - isolation & purification Pseudomonas Infections - complications Pseudomonas Infections - diagnosis Pseudomonas Infections - drug therapy Pseudomonas Infections - microbiology Soil erosion Thyroid Cartilage - diagnostic imaging Thyroid Cartilage - microbiology Thyroid gland Tomography, X-Ray Computed Treatment Outcome Tuberculosis Tuberculosis, Laryngeal - diagnosis Vocal Cords - diagnostic imaging Vocal Cords - microbiology |
| title | Pseudomonas laryngeal perichondritis: unexpected diagnosis |
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