Hepatitis B core‐related antigen levels predict recurrence‐free survival in patients with HBV‐associated early‐stage hepatocellular carcinoma: results from a Dutch long‐term follow‐up study

Prognosis of hepatitis B (HBV)‐associated hepatocellular carcinoma (HCC) is poor due to high rates of HCC recurrence and progression of underlying liver disease. We studied whether serum hepatitis B core‐related antigen (HBcrAg) levels could predict HCC recurrence and outcome in HBV associated. High...

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Veröffentlicht in:Journal of viral hepatitis 2021-01, Vol.28 (1), p.205-208
Hauptverfasser: Beudeker, Boris J. B., Groothuismink, Zwier M. A., Man, Robert A., Witjes, Caroline D. M., Eijk, Annemiek A., Boonstra, Andre, Sonneveld, Milan J.
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container_end_page 208
container_issue 1
container_start_page 205
container_title Journal of viral hepatitis
container_volume 28
creator Beudeker, Boris J. B.
Groothuismink, Zwier M. A.
Man, Robert A.
Witjes, Caroline D. M.
Eijk, Annemiek A.
Boonstra, Andre
Sonneveld, Milan J.
description Prognosis of hepatitis B (HBV)‐associated hepatocellular carcinoma (HCC) is poor due to high rates of HCC recurrence and progression of underlying liver disease. We studied whether serum hepatitis B core‐related antigen (HBcrAg) levels could predict HCC recurrence and outcome in HBV associated. Higher HBcrAg levels at HCC diagnosis were independently associated with reduced overall and recurrence‐free survival in patients with early, but not advanced, stage HCC.
doi_str_mv 10.1111/jvh.13394
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source Wiley Journals
subjects Antigens
HBcrAg
Hepatitis B
Hepatocellular carcinoma
Liver cancer
Liver diseases
Medical prognosis
Short Communication
Survival
title Hepatitis B core‐related antigen levels predict recurrence‐free survival in patients with HBV‐associated early‐stage hepatocellular carcinoma: results from a Dutch long‐term follow‐up study
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