Molecular Epidemiology of Escherichia coli Producing CTX-M and pAmpC β-Lactamases from Dairy Farms Identifies a Dominant Plasmid Encoding CTX-M-32 but No Evidence for Transmission to Humans in the Same Geographical Region

Third-generation cephalosporin resistance (3GC-R) in is a rising problem in human and farmed-animal populations. We conducted whole-genome sequencing analysis of 138 representative 3GC-R isolates previously collected from dairy farms in southwest England and confirmed by PCR to carry acquired 3GC-R...

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Veröffentlicht in:	Applied and environmental microbiology 2020-12, Vol.87 (1), p.1
Hauptverfasser:	Findlay, Jacqueline, Mounsey, Oliver, Lee, Winnie W Y, Newbold, Nerissa, Morley, Katy, Schubert, Hannah, Gould, Virginia C, Cogan, Tristan A, Reyher, Kristen K, Avison, Matthew B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal populations Animals beta-Lactamases - genetics beta-Lactamases - metabolism Cattle Cattle Diseases - epidemiology Cattle Diseases - transmission Cephalosporins Conserved sequence Dairy cattle Dairy farming Dairy farms E coli England - epidemiology Epidemiology Escherichia coli Escherichia coli - enzymology Escherichia coli - genetics Escherichia coli - physiology Escherichia coli Infections - epidemiology Escherichia coli Infections - transmission Escherichia coli Infections - veterinary Farms Gene sequencing Genomes Geographical distribution Geographical locations Molecular Epidemiology Phylogeny Plasmids Plasmids - genetics Plasmids - metabolism Public and Environmental Health Microbiology Whole genome sequencing β Lactamase
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