Temporizing management vs immediate delivery in early‐onset severe preeclampsia between 28 and 34 weeks of gestation (TOTEM study): An open‐label randomized controlled trial

Introduction There is little evidence to guide the timing of delivery of women with early‐onset severe preeclampsia. We hypothesize that immediate delivery is not inferior for neonatal outcome but reduces maternal complications compared with temporizing management. Material and methods This Dutch mu...

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Veröffentlicht in:	Acta obstetricia et gynecologica Scandinavica 2021-01, Vol.100 (1), p.109-118
Hauptverfasser:	Duvekot, Johannes J., Duijnhoven, Ruben G., Horen, Eva, Bax, Caroline J., Bloemenkamp, Kitty W., Brussé, Ingrid A., Dijk, Peter H., Franssen, Maureen T., Franx, Arie, Oudijk, Martijn A., Porath, Martina M., Scheepers, Hubertina C., Wassenaer‐Leemhuis, Aleid G., Drongelen, Joris, Mol, Ben W., Ganzevoort, Wessel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Clinical outcomes Clinical trials Delivery, Obstetric - methods Disease management early‐onset preeclampsia Female Gestational Age Humans maternal morbidity neonatal morbidity Netherlands Newborn babies Original Pre-Eclampsia - therapy Preeclampsia Pregnancy Pregnancy complications Pregnancy Outcome temporizing management
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