A research of STEAP1 regulated gastric cancer cell proliferation, migration and invasion in vitro and in vivos

Six‐Transmembrane Epithelial Antigene of the Prostate 1 (STEAP1) is associated with the occurrence and development of cancer. This study aimed to clarify the role of STEAP1 in gastric cancer tumour growth and metastasis, as well as its molecular mechanism of action.Statistical methods were used for...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2020-12, Vol.24 (24), p.14217-14230
Hauptverfasser:	Zhang, Zhe, Hou, Wen‐bin, Zhang, Chao, Tan, Yu‐en, Zhang, Dong‐dong, An, Wen, Pan, Si‐wei, Wu, Wan‐di, Chen, Qing‐chuan, Xu, Hui‐mian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged AKT protein Animal research Animals Antibodies Antigens Antigens, Neoplasm - genetics Antigens, Neoplasm - metabolism Biomarkers, Tumor Cell culture Cell growth Cell Line, Tumor Cell migration Cell Movement - genetics Cell proliferation Cell Proliferation - genetics Cholecystokinin Disease Models, Animal Epithelial-Mesenchymal Transition - genetics Ewings sarcoma Experiments Female Flow cytometry FOXO1 protein Gastric cancer Gene Expression Genes Heterografts Humans Immunohistochemistry invasion Kaplan-Meier Estimate Laboratory animals Male Medical research Mesenchyme Metastases Mice Middle Aged migration Molecular modelling Neoplasm Invasiveness - genetics Original Oxidoreductases - genetics Oxidoreductases - metabolism Peritoneum Polymerase chain reaction Prognosis proliferation Prostate Prostate cancer Proteins Reverse transcription STEAP1 Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - mortality Stomach Neoplasms - pathology Transfection Tumor Burden Tumor cell lines Tumorigenesis Tumors Wound healing
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