Effect of EZH2 on pulmonary artery smooth muscle cell migration in pulmonary hypertension

Pulmonary hypertension (PH) is a life‑threatening disease that often involves vascular remodeling. Although pulmonary arterial smooth muscle cells (PASMCs) are the primary participants in vascular remodeling, their biological role is not entirely clear. The present study analyzed the role of enhance...

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Veröffentlicht in:	Molecular medicine reports 2021-02, Vol.23 (2), Article 129
Hauptverfasser:	Wang, Ying, Huang, Xiao-Xi, Leng, Dong, Li, Ji-Feng, Liang, Yan, Jiang, Tao
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cell adhesion & migration Cell culture Cell growth Cell Line Cell migration Cell Movement - genetics Development and progression Disease DNA microarrays Enhancer of Zeste Homolog 2 Protein - biosynthesis Enhancer of Zeste Homolog 2 Protein - genetics Epigenetics Female Gene expression Gene Expression Regulation Gene Knockdown Techniques Gene Ontology Genomes Health aspects Humans Hypertension Hypertension, Pulmonary - chemically induced Hypertension, Pulmonary - genetics Hypertension, Pulmonary - metabolism Hypoxia Inflammation Inflammation - genetics Inflammation - immunology Laboratories Male Medical imaging Methyltransferases Middle Aged Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - metabolism Myocytes, Smooth Muscle - cytology Myocytes, Smooth Muscle - metabolism NADPH Oxidase 1 - metabolism Oxidoreductase Oxidoreductases - metabolism Pathogenesis Patients Physiological aspects Pulmonary arteries Pulmonary artery Pulmonary Artery - metabolism Pulmonary hypertension Smooth muscle Superoxide dismutase Superoxide Dismutase - metabolism Thromboembolism Tissue Array Analysis Transcriptome Vascular Remodeling - genetics Veins & arteries Wound healing
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