FHOD formin and SRF promote post-embryonic striated muscle growth through separate pathways in C. elegans

Previous work with cultured cells has shown transcription of muscle genes by serum response factor (SRF) can be stimulated by actin polymerization driven by proteins of the formin family. However, it is not clear if endogenous formins similarly promote SRF-dependent transcription during muscle devel...

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Veröffentlicht in:	Experimental cell research 2021-01, Vol.398 (1), p.112388-112388, Article 112388
Hauptverfasser:	Yingling, Curtis V., Pruyne, David
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES ACTIN ANIMALS Caenorhabditis elegans Caenorhabditis elegans - embryology Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism CELL CULTURES Cell Proliferation FHOD-1 Formin Formins - genetics Formins - metabolism GENES IN VIVO INHIBITION Muscle, Striated - metabolism MUSCLES MUTANTS MYOSIN POLYMERIZATION Proteasome PROTEOLYSIS Serum response factor Serum Response Factor - genetics Serum Response Factor - metabolism Striated muscle TRANSCRIPTION
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