Volumetric analysis of IDH-mutant lower-grade glioma: a natural history study of tumor growth rates before and after treatment

Abstract Background Lower-grade gliomas (LGGs) with isocitrate dehydrogenase 1 and/or 2 (IDH1/2) mutations have long survival times, making evaluation of treatment efficacy difficult. We investigated the volumetric growth rate of IDH mutant gliomas before and after treatment with established glioma...

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2020-12, Vol.22 (12), p.1822-1830
Hauptverfasser:	Huang, Raymond Y, Young, Robert J, Ellingson, Benjamin M, Veeraraghavan, Harini, Wang, Wei, Tixier, Florent, Um, Hyemin, Nawaz, Rasheed, Luks, Tracy, Kim, John, Gerstner, Elizabeth R, Schiff, David, Peters, Katherine B, Mellinghoff, Ingo K, Chang, Susan M, Cloughesy, Timothy F, Wen, Patrick Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brain Neoplasms - diagnostic imaging Brain Neoplasms - drug therapy Brain Neoplasms - genetics Clinical Investigations Glioma - diagnostic imaging Glioma - drug therapy Glioma - genetics Humans Isocitrate Dehydrogenase - genetics Magnetic Resonance Imaging Mutation Neoplasm Grading Retrospective Studies
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