Properties and biological impact of RNA G-quadruplexes: from order to turmoil and back

Abstract Guanine-quadruplexes (G4s) are non-canonical four-stranded structures that can be formed in guanine (G) rich nucleic acid sequences. A great number of G-rich sequences capable of forming G4 structures have been described based on in vitro analysis, and evidence supporting their formation in...

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Veröffentlicht in:Nucleic acids research 2020-12, Vol.48 (22), p.12534-12555
Hauptverfasser: Kharel, Prakash, Becker, Gertraud, Tsvetkov, Vladimir, Ivanov, Pavel
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Sprache:eng
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