Monocyte phenotyping and management of lipoprotein X syndrome

Accumulation of lipoprotein X (LpX) in blood can cause severe hypercholesterolemia and cutaneous xanthomas. Monocytes sensitively sense lipid changes in circulation and contribute to inflammation. However, how monocytes respond to LpX is undefined. We examined the phenotype of monocytes from a patie...

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Veröffentlicht in:	Journal of clinical lipidology 2020-11, Vol.14 (6), p.850-858
Hauptverfasser:	Lian, Zeqin, Saeed, Anum, Peng, Xueying, Perrard, Xiaoyuan Dai, Jia, Xiaoming, Hussain, Aliza, Ballantyne, Christie M., Wu, Huaizhu
Format:	Artikel
Sprache:	eng
Schlagworte:	Foamy monocyte Humans Hypercholesterolemia Hypercholesterolemia - blood Hypercholesterolemia - immunology Lipoprotein X Lipoprotein-X - blood Monocytes - cytology Phenotype Primary biliary cirrhosis
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