Clinical features, prognostic factors, and antibody effects in anti-mGluR1 encephalitis

OBJECTIVETo clinically characterize patients with anti-metabotropic glutamate receptor (mGluR) 1 encephalitis, to identify prognostic factors, and to study the immunoglobulin G (IgG) subclasses and effects of antibodies on neuronal mGluR1 clusters. METHODSClinical information on new and previously r...

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Veröffentlicht in:	Neurology 2020-12, Vol.95 (22), p.e3012-e3025
Hauptverfasser:	Spatola, Marianna, Petit Pedrol, Mar, Maudes, Estibaliz, Simabukuro, Mateus, Muñiz-Castrillo, Sergio, Pinto, Anne-Laurie, Wandinger, Klaus-Peter, Spiegler, Juliane, Schramm, Peter, Dutra, Lívia Almeida, Iorio, Raffaele, Kornblum, Cornelia, Bien, Christian G., Höftberger, Romana, Leypoldt, Frank, Titulaer, Maarten J., Sillevis Smitt, Peter, Honnorat, Jérôme, Rosenfeld, Myrna R., Graus, Francesc, Dalmau, Josep
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Animals Atrophy - pathology Autoantibodies - immunology Autoimmune Diseases of the Nervous System - complications Autoimmune Diseases of the Nervous System - diagnosis Autoimmune Diseases of the Nervous System - immunology Cells, Cultured Cerebellar Diseases - diagnosis Cerebellar Diseases - etiology Cerebellar Diseases - immunology Cerebellar Diseases - pathology Child Embryo, Mammalian Encephalitis - complications Encephalitis - diagnosis Encephalitis - immunology Female Follow-Up Studies Hippocampus - cytology Humans Immunoglobulin G - classification Immunotherapy Magnetic Resonance Imaging Male Middle Aged Neurons Prognosis Rats Receptors, Metabotropic Glutamate - immunology
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