Unbiased optical mapping of telomere-integrated endogenous human herpesvirus 6

Next-generation sequencing technologies allowed sequencing of thousands of genomes. However, there are genomic regions that remain difficult to characterize, including telomeres, centromeres, and other low-complexity regions, as well as transposable elements and endogenous viruses. Human herpesvirus...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2020-12, Vol.117 (49), p.31410-31416
Hauptverfasser:	Wight, Darren J., Aimola, Giulia, Aswad, Amr, Lai, Chi-Yu Jill, Bahamon, Christian, Hong, Karl, Hill, Joshua A., Kaufer, Benedikt B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences Centromeres Chromosomes Chromosomes, Human - genetics Complexity Gene mapping Genetic structure Genome, Viral Genomes Genomic analysis Germ cells Herpesvirus 6, Human - genetics Herpesvirus 6, Human - physiology Host-Pathogen Interactions Humans Integration Loci Mapping Next-generation sequencing Optical Imaging Technology utilization Telomerase Telomere - metabolism Telomere Homeostasis Telomeres Viruses
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