Single-cell genomics to understand disease pathogenesis

Cells are minimal functional units in biological phenomena, and therefore single-cell analysis is needed to understand the molecular behavior leading to cellular function in organisms. In addition, omics analysis technology can be used to identify essential molecular mechanisms in an unbiased manner...

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Veröffentlicht in:	Journal of human genetics 2021-01, Vol.66 (1), p.75-84
1. Verfasser:	Nomura, Seitaro
Format:	Artikel
Sprache:	eng
Schlagworte:	Epigenomics - methods Gene Expression Profiling - methods Genome, Human - genetics Genomics Genomics - methods Genotyping Techniques - methods Heart Failure - diagnosis Heart Failure - genetics Heart Failure - therapy Humans Molecular modelling Myocytes, Cardiac - cytology Myocytes, Cardiac - metabolism Pathogenesis Review RNA-Seq - methods Single-Cell Analysis - methods
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