The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review

•Pheochromocytoma is a tumor developed at the expense of chromaffin tissues.•Extra-adrenal localization of pheochromocytoma is rare.•The main problem with these tumors is to affirm their benignity or malignancy.•Ectopic pheochromocytomas have a malignant development once in two.•Ectopic pheochromocy...

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Veröffentlicht in:International journal of surgery case reports 2020-01, Vol.77, p.857-861
Hauptverfasser: Jandou, Issam, Moataz, Amine, Mouqtassid, Mohammed Hicham, Dakir, Mohammed, Debbagh, Adil, Aboutaieb, Rachid
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container_title International journal of surgery case reports
container_volume 77
creator Jandou, Issam
Moataz, Amine
Mouqtassid, Mohammed Hicham
Dakir, Mohammed
Debbagh, Adil
Aboutaieb, Rachid
description •Pheochromocytoma is a tumor developed at the expense of chromaffin tissues.•Extra-adrenal localization of pheochromocytoma is rare.•The main problem with these tumors is to affirm their benignity or malignancy.•Ectopic pheochromocytomas have a malignant development once in two.•Ectopic pheochromocytoma presents a diagnostic and therapeutic dilemma. Extra-adrenal localization of pheochromocytoma is rare. Its clinical revelation is paroxysmal but maybe in the form of permanent hypertension resistant to treatment. The main problem with these tumors is to affirm their benignity or malignancy, ectopic pheochromocytomas have a malignant development once in two. We report the observation of a 39-year-old woman hypertensive on Amlodipine. She presents for sweating, headache, and palpation. The dosage of urinary metabolites revealed a marked increase in metanephrine and normetanephrine. Imagery had shown, at the expense of the left lateral wall of the bladder, a budding tissue formation with irregular contours which was significantly enhanced after injection of PDC. The diagnosis of an ectopic pheochromocytoma was accepted. The patient underwent a partial cystectomy, the postoperative consequences of which were unremarkable. Threatening secretory syndromes are rare medical situations that require urgent management. Pheochromocytoma can be seen at any age from childhood to old age. The treatment of pheochromocytoma is surgical, once the stages of positive and topographic diagnosis have been carried out, the patient must be immediately entrusted to a team of trained surgeons and anesthetists. The prognosis remains unpredictable, hence the interest in prolonged monitoring. Pheochromocytoma is a tumor developed at the expense of chromaffin tissues, extra-adrenal localizations exist, but remain rare. It is a pathology that presents a diagnostic and therapeutic dilemma in which patients require regular and prolonged postoperative monitoring to detect a possible metastasis or recurrence.
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Extra-adrenal localization of pheochromocytoma is rare. Its clinical revelation is paroxysmal but maybe in the form of permanent hypertension resistant to treatment. The main problem with these tumors is to affirm their benignity or malignancy, ectopic pheochromocytomas have a malignant development once in two. We report the observation of a 39-year-old woman hypertensive on Amlodipine. She presents for sweating, headache, and palpation. The dosage of urinary metabolites revealed a marked increase in metanephrine and normetanephrine. Imagery had shown, at the expense of the left lateral wall of the bladder, a budding tissue formation with irregular contours which was significantly enhanced after injection of PDC. The diagnosis of an ectopic pheochromocytoma was accepted. The patient underwent a partial cystectomy, the postoperative consequences of which were unremarkable. Threatening secretory syndromes are rare medical situations that require urgent management. Pheochromocytoma can be seen at any age from childhood to old age. The treatment of pheochromocytoma is surgical, once the stages of positive and topographic diagnosis have been carried out, the patient must be immediately entrusted to a team of trained surgeons and anesthetists. The prognosis remains unpredictable, hence the interest in prolonged monitoring. Pheochromocytoma is a tumor developed at the expense of chromaffin tissues, extra-adrenal localizations exist, but remain rare. 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Extra-adrenal localization of pheochromocytoma is rare. Its clinical revelation is paroxysmal but maybe in the form of permanent hypertension resistant to treatment. The main problem with these tumors is to affirm their benignity or malignancy, ectopic pheochromocytomas have a malignant development once in two. We report the observation of a 39-year-old woman hypertensive on Amlodipine. She presents for sweating, headache, and palpation. The dosage of urinary metabolites revealed a marked increase in metanephrine and normetanephrine. Imagery had shown, at the expense of the left lateral wall of the bladder, a budding tissue formation with irregular contours which was significantly enhanced after injection of PDC. The diagnosis of an ectopic pheochromocytoma was accepted. The patient underwent a partial cystectomy, the postoperative consequences of which were unremarkable. Threatening secretory syndromes are rare medical situations that require urgent management. 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source Elsevier ScienceDirect Journals Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Bladder pheochromocytoma
Case Report
Ectopic pheochromocytoma
Methoxylated derivative
Partial cystectomy
title The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review
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