Embryonic Stem Cell Differentiation Is Regulated by SET through Interactions with p53 and β-Catenin

The multifunctional histone chaperone, SET, is essential for embryonic development in the mouse. Previously, we identified SET as a factor that is rapidly downregulated during embryonic stem cell (ESC) differentiation, suggesting a possible role in the maintenance of pluripotency. Here, we explore S...

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Veröffentlicht in:	Stem cell reports 2020-12, Vol.15 (6), p.1260-1274
Hauptverfasser:	Harikumar, Arigela, Lim, Patrick S.L., Nissim-Rafinia, Malka, Park, Jung Eun, Sze, Siu Kwan, Meshorer, Eran
Format:	Artikel
Sprache:	eng
Schlagworte:	chromatin differentiation embryonic stem cells epigenetics p53 pluripotency Wnt β-catenin
Online-Zugang:	Volltext
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