Thirst recruits phasic dopamine signaling through subfornical organ neurons

Thirst is a highly potent drive that motivates organisms to seek out and consume balance-restoring stimuli. The detection of dehydration is well understood and involves signals of peripheral origin and the sampling of internal milieu by first order homeostatic neurons within the lamina terminalis—pa...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2020-12, Vol.117 (48), p.30744-30754
Hauptverfasser:	Hsu, Ted M., Bazzino, Paula, Hurh, Samantha J., Konanur, Vaibhav R., Roitman, Jamie D., Roitman, Mitchell F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin Angiotensin II Animals Behavior, Animal Biological Sciences Biomarkers Cues Dehydration Dopamine Dopamine - metabolism Dopaminergic Neurons - metabolism Electrophysiological Phenomena Evoked Potentials Female Ghrelin Glutamatergic transmission Hunger Immunohistochemistry Information processing Male Mesolimbic system Motivation Neurons Photometry Rats Reinforcement Reinforcement, Psychology Signal Transduction Signaling Stimuli Subfornical organ Subfornical Organ - metabolism Thirst Ventral tegmentum
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