EPEN-25. EXCEPTIONAL CLINICAL AND IMAGING RESPONSE TO TRK-INHIBITION IN A PATIENT WITH SUPRATENTORIAL EPENDYMOMA HARBORING NTRK2 GENE FUSION

Abstract BACKGROUND Patients with metastatic pediatric ependymoma have limited therapeutic options and poor outcomes. Approximately ¾ of supratentorial ependymomas are driven by C11ORF95-RELA fusions, and the remaining by a heterogeneous group of fusion events. We present a six year-old male diagnos...

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Veröffentlicht in:Neuro-oncology (Charlottesville, Va.) Va.), 2020-12, Vol.22 (Supplement_3), p.iii312-iii313
Hauptverfasser: Mangum, Ross, Reuther, Jacquelyn, Adesina, Adekunle, Kukreja, Marcia, Curry, Daniel, Malbari, Fatema, Chintagumpala, Murali, Muzny, Donna M, Fisher, Kevin, Roy, Angshumoy, Bertrand, Kelsey C, Mack, Stephen C, Plon, Sharon E, Parsons, D Williams, Lin, Frank Y
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Sprache:eng
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