Network Pharmacology-Based Study on the Mechanism of Gegen Qinlian Decoction against Colorectal Cancer

Purpose. Gegen Qinlian decoction (GQD) has been used to treat gastrointestinal diseases, such as diarrhea and ulcerative colitis (UC). A recent study demonstrated that GQD enhanced the effect of PD-1 blockade in colorectal cancer (CRC). This study used network pharmacology analysis to investigate th...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2020, Vol.2020 (2020), p.1-14
Hauptverfasser:	Li, Hulun, Fan, Yujing, Chen, Jing, Guan, Jingming, Guo, Lin, Fan, Qiaowei, Chen, Zhendong
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer therapies Chemokines Chinese medicine Colorectal cancer Colorectal carcinoma Coronaviruses COVID-19 Diarrhea Gastrointestinal diseases Gene expression Genomes Inflammatory bowel disease Interleukin 17 Medical research NF-κB protein PD-1 protein Pharmacology Prostaglandins Protein interaction Proteins Quercetin Toll-like receptors Traditional Chinese medicine Ulcerative colitis
Online-Zugang:	Volltext
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