Mendelian Randomization Analysis of n-6 Polyunsaturated Fatty Acid Levels and Pancreatic Cancer Risk

Background: Whether circulating polyunsaturated fatty acid (PUFA) levels are associated with pancreatic cancer risk is uncertain. Mendelian randomization (MR) represents a study design using genetic instruments to better characterize the relationship between exposure and outcome. Methods: We utilize...

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Veröffentlicht in:Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2020-12, Vol.29 (12), p.2735-2739
Hauptverfasser: Ghoneim, Dalia H., Zhu, Jingjing, Zheng, Wei, Long, Jirong, Murff, Harvey J., Ye, Fei, Setiawan, Veronica Wendy, Wilkens, Lynne R., Khankari, Nikhil K., Haycock, Philip, Antwi, Samuel O., Yang, Yaohua, Arslan, Alan A., Freeman, Laura E. Beane, Bracci, Paige M., Canzian, Federico, Du, Mengmeng, Gallinger, Steven, Giles, Graham G., Goodman, Phyllis J., Kooperberg, Charles, Le Marchand, Loic, Neale, Rachel E., Scelo, Ghislaine, Visvanathan, Kala, White, Emily, Albanes, Demetrius, Amiano, Pilar, Andreotti, Gabriella, Babic, Ana, Bamlet, William R., Berndt, Sonja I., Brais, Lauren K., Brennan, Paul, Bueno-De-Mesquita, Bas, Buring, Julie E., Campbell, Peter T., Rabe, Kari G., Chanock, Stephen J., Duggal, Priya, Fuchs, Charles S., Gaziano, J. Michael, Goggins, Michael G., Hackert, Thilo, Hassan, Manal M., Helzlsouer, Kathy J., Holly, Elizabeth A., Hoover, Robert N., Katske, Verena, Kurtz, Robert C., Lee, I-Min, Malats, Nuria, Milne, Roger L., Murphy, Neil, Oberg, Ann L., Porta, Miquel, Rothman, Nathaniel, Sesso, Howard D., Silverman, Debra T., Thompson, Ian M., Wactawski-Wende, Jean, Wang, Xiaoliang, Wentzensen, Nicolas, Yu, Herbert, Zeleniuch-Jacquotte, Anne, Yu, Kai, Wolpin, Brian M., Jacobs, Eric J., Duell, Eric J., Risch, Harvey A., Petersen, Gloria M., Amundadottir, Laufey T., Kraft, Peter, Klein, Alison P., Stolzenberg-Solomon, Rachel Z., Shu, Xiao-Ou, Wu, Lang
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