Methnaridine is an orally bioavailable, fast‐killing and long‐acting antimalarial agent that cures Plasmodium infections in mice

Background and Purpose Malaria is one of the deadliest diseases in the world. Novel chemotherapeutic agents are urgently required to combat the widespread Plasmodium resistance to frontline drugs. Here, we report the discovery of a novel benzonaphthyridine antimalarial, methnaridine, which was ident...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:British journal of pharmacology 2020-12, Vol.177 (24), p.5569-5579
Hauptverfasser: Wang, Weisi, Yao, Junmin, Chen, Zhuo, Sun, Yiming, Shi, Yuqing, Wei, Yufen, Zhou, Hejun, Yu, Yingfang, Li, Shizhu, Duan, Liping
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!