Function and therapeutic potential of G protein‐coupled receptors in epididymis

Infertility rates for both females and males have increased continuously in recent years. Currently, effective treatments for male infertility with defined mechanisms or targets are still lacking. G protein‐coupled receptors (GPCRs) are the largest class of drug targets, but their functions and the...

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Veröffentlicht in:	British journal of pharmacology 2020-12, Vol.177 (24), p.5489-5508
Hauptverfasser:	Zhang, Daolai, Wang, Yanfei, Lin, Hui, Sun, Yujing, Wang, Mingwei, Jia, Yingli, Yu, Xiao, Jiang, Hui, Xu, Wenming, Sun, Jin‐Peng, Xu, Zhigang
Format:	Artikel
Sprache:	eng
Schlagworte:	ADGRG2 AT2 receptor Epididymis G protein-coupled receptors G protein‐coupled receptor (GPCR) Genetic diversity Homeostasis Infertility LGR4 male infertility Receptor mechanisms Review Therapeutic targets
Online-Zugang:	Volltext
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