Delivery of high-dose radiation for recurrence of breast cancer in a patient with hidradenitis suppurativa

Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterised by inflammatory nodules, abscesses, sinus tract formation and scarring. There is a lack of evidence for the use of radical radiotherapy for patients with a diagnosis of HS. A 56-year-old woman with a long-standing d...

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Veröffentlicht in:BMJ case reports 2020-11, Vol.13 (11), p.e238848
Hauptverfasser: Rozati, Hamoun, Ferguson, Felicity J, Rashidghamat, Ellie, Anand, Girija
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creator Rozati, Hamoun
Ferguson, Felicity J
Rashidghamat, Ellie
Anand, Girija
description Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterised by inflammatory nodules, abscesses, sinus tract formation and scarring. There is a lack of evidence for the use of radical radiotherapy for patients with a diagnosis of HS. A 56-year-old woman with a long-standing diagnosis of HS presented with a cutaneous local recurrence of breast cancer. Radical radiotherapy was offered despite issues with previous prolonged postoperative wound healing associated with the underlying HS. A multidisciplinary evaluation was conducted with breast surgeons, dermatologists and radiation oncologists to assess the safety of delivery of radical radiotherapy. Five weeks post radiotherapy, the patient had no significant residual symptoms from her breast cancer treatment for her HS and no escalation of treatment was required for her HS. Factors contributing to safe delivery of radical radiotherapy include medical optimisation prior to and during treatment, radiation dose, radiation technique and vigilant post-treatment surveillance.
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There is a lack of evidence for the use of radical radiotherapy for patients with a diagnosis of HS. A 56-year-old woman with a long-standing diagnosis of HS presented with a cutaneous local recurrence of breast cancer. Radical radiotherapy was offered despite issues with previous prolonged postoperative wound healing associated with the underlying HS. A multidisciplinary evaluation was conducted with breast surgeons, dermatologists and radiation oncologists to assess the safety of delivery of radical radiotherapy. Five weeks post radiotherapy, the patient had no significant residual symptoms from her breast cancer treatment for her HS and no escalation of treatment was required for her HS. 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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Abscesses
Antibiotics
Breast cancer
Breast Neoplasms - complications
Breast Neoplasms - radiotherapy
Cancer therapies
Case Report
Case reports
Chronic illnesses
Dermatology
Dose Fractionation, Radiation
Female
Hidradenitis Suppurativa - complications
Humans
Mastectomy
Medical imaging
Metabolic syndrome
Middle Aged
Neoplasm Recurrence, Local - radiotherapy
Pathogenesis
Patients
Radiation Dosage
Radiation therapy
Radiotherapy
Radiotherapy - adverse effects
Scars
Sinuses
Skin
Skin - radiation effects
Ulcers
title Delivery of high-dose radiation for recurrence of breast cancer in a patient with hidradenitis suppurativa
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