Delivery of high-dose radiation for recurrence of breast cancer in a patient with hidradenitis suppurativa
Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterised by inflammatory nodules, abscesses, sinus tract formation and scarring. There is a lack of evidence for the use of radical radiotherapy for patients with a diagnosis of HS. A 56-year-old woman with a long-standing d...
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description | Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterised by inflammatory nodules, abscesses, sinus tract formation and scarring. There is a lack of evidence for the use of radical radiotherapy for patients with a diagnosis of HS. A 56-year-old woman with a long-standing diagnosis of HS presented with a cutaneous local recurrence of breast cancer. Radical radiotherapy was offered despite issues with previous prolonged postoperative wound healing associated with the underlying HS. A multidisciplinary evaluation was conducted with breast surgeons, dermatologists and radiation oncologists to assess the safety of delivery of radical radiotherapy. Five weeks post radiotherapy, the patient had no significant residual symptoms from her breast cancer treatment for her HS and no escalation of treatment was required for her HS. Factors contributing to safe delivery of radical radiotherapy include medical optimisation prior to and during treatment, radiation dose, radiation technique and vigilant post-treatment surveillance. |
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There is a lack of evidence for the use of radical radiotherapy for patients with a diagnosis of HS. A 56-year-old woman with a long-standing diagnosis of HS presented with a cutaneous local recurrence of breast cancer. Radical radiotherapy was offered despite issues with previous prolonged postoperative wound healing associated with the underlying HS. A multidisciplinary evaluation was conducted with breast surgeons, dermatologists and radiation oncologists to assess the safety of delivery of radical radiotherapy. Five weeks post radiotherapy, the patient had no significant residual symptoms from her breast cancer treatment for her HS and no escalation of treatment was required for her HS. Factors contributing to safe delivery of radical radiotherapy include medical optimisation prior to and during treatment, radiation dose, radiation technique and vigilant post-treatment surveillance.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2020-238848</identifier><identifier>PMID: 33257394</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd</publisher><subject>Abscesses ; Antibiotics ; Breast cancer ; Breast Neoplasms - complications ; Breast Neoplasms - radiotherapy ; Cancer therapies ; Case Report ; Case reports ; Chronic illnesses ; Dermatology ; Dose Fractionation, Radiation ; Female ; Hidradenitis Suppurativa - complications ; Humans ; Mastectomy ; Medical imaging ; Metabolic syndrome ; Middle Aged ; Neoplasm Recurrence, Local - radiotherapy ; Pathogenesis ; Patients ; Radiation Dosage ; Radiation therapy ; Radiotherapy ; Radiotherapy - adverse effects ; Scars ; Sinuses ; Skin ; Skin - radiation effects ; Ulcers</subject><ispartof>BMJ case reports, 2020-11, Vol.13 (11), p.e238848</ispartof><rights>BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2020 BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b422t-3c00a8edcdc235fb567c4808af3fcf91d2bd34b6b4a9ccecc32db24946c786333</citedby><cites>FETCH-LOGICAL-b422t-3c00a8edcdc235fb567c4808af3fcf91d2bd34b6b4a9ccecc32db24946c786333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705580/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705580/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33257394$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rozati, Hamoun</creatorcontrib><creatorcontrib>Ferguson, Felicity J</creatorcontrib><creatorcontrib>Rashidghamat, Ellie</creatorcontrib><creatorcontrib>Anand, Girija</creatorcontrib><title>Delivery of high-dose radiation for recurrence of breast cancer in a patient with hidradenitis suppurativa</title><title>BMJ case reports</title><addtitle>BMJ Case Rep</addtitle><addtitle>BMJ Case Rep</addtitle><description>Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterised by inflammatory nodules, abscesses, sinus tract formation and scarring. There is a lack of evidence for the use of radical radiotherapy for patients with a diagnosis of HS. A 56-year-old woman with a long-standing diagnosis of HS presented with a cutaneous local recurrence of breast cancer. Radical radiotherapy was offered despite issues with previous prolonged postoperative wound healing associated with the underlying HS. A multidisciplinary evaluation was conducted with breast surgeons, dermatologists and radiation oncologists to assess the safety of delivery of radical radiotherapy. Five weeks post radiotherapy, the patient had no significant residual symptoms from her breast cancer treatment for her HS and no escalation of treatment was required for her HS. Factors contributing to safe delivery of radical radiotherapy include medical optimisation prior to and during treatment, radiation dose, radiation technique and vigilant post-treatment surveillance.</description><subject>Abscesses</subject><subject>Antibiotics</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - complications</subject><subject>Breast Neoplasms - radiotherapy</subject><subject>Cancer therapies</subject><subject>Case Report</subject><subject>Case reports</subject><subject>Chronic illnesses</subject><subject>Dermatology</subject><subject>Dose Fractionation, Radiation</subject><subject>Female</subject><subject>Hidradenitis Suppurativa - complications</subject><subject>Humans</subject><subject>Mastectomy</subject><subject>Medical imaging</subject><subject>Metabolic syndrome</subject><subject>Middle Aged</subject><subject>Neoplasm Recurrence, Local - radiotherapy</subject><subject>Pathogenesis</subject><subject>Patients</subject><subject>Radiation Dosage</subject><subject>Radiation therapy</subject><subject>Radiotherapy</subject><subject>Radiotherapy - adverse effects</subject><subject>Scars</subject><subject>Sinuses</subject><subject>Skin</subject><subject>Skin - radiation effects</subject><subject>Ulcers</subject><issn>1757-790X</issn><issn>1757-790X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkc9LwzAYhoMoOubO3iTgTammSdqmF0H8DQMvCt5CkqZbxtbUL-3E_96MzakHwVyS8D158sKL0FFKztOU5RfaQEIJJQllQnCxgwZpkRVJUZLX3R_nAzQKYUbiYikXnO2jA8ZoVrCSD9Dsxs7d0sIH9jWeusk0qXywGFTlVOd8g2sPGKzpAWxj7IrSYFXosFHxDtg1WOE2srbp8LvrptFSxee2cZ0LOPRt20McL9Uh2qvVPNjRZh-il7vb5-uHZPx0_3h9NU40p7RLmCFECVuZylCW1TrLC8MFEapmtanLtKK6YlznmqvSGGsMo5WmvOS5KUTOGBuiy7W37fUiemIwUHPZglso-JBeOfl70ripnPilLAqSZYJEwclGAP6tt6GTM99DEzNLyvMsz0pKVtTFmjLgQwBbb39IiVz1I2M_ctWPXPcTXxz_DLblv9qIwOka0IvZP2xn3_A24F_0J5h3qUw</recordid><startdate>20201130</startdate><enddate>20201130</enddate><creator>Rozati, Hamoun</creator><creator>Ferguson, Felicity J</creator><creator>Rashidghamat, Ellie</creator><creator>Anand, Girija</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20201130</creationdate><title>Delivery of high-dose radiation for recurrence of breast cancer in a patient with hidradenitis suppurativa</title><author>Rozati, Hamoun ; 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There is a lack of evidence for the use of radical radiotherapy for patients with a diagnosis of HS. A 56-year-old woman with a long-standing diagnosis of HS presented with a cutaneous local recurrence of breast cancer. Radical radiotherapy was offered despite issues with previous prolonged postoperative wound healing associated with the underlying HS. A multidisciplinary evaluation was conducted with breast surgeons, dermatologists and radiation oncologists to assess the safety of delivery of radical radiotherapy. Five weeks post radiotherapy, the patient had no significant residual symptoms from her breast cancer treatment for her HS and no escalation of treatment was required for her HS. Factors contributing to safe delivery of radical radiotherapy include medical optimisation prior to and during treatment, radiation dose, radiation technique and vigilant post-treatment surveillance.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd</pub><pmid>33257394</pmid><doi>10.1136/bcr-2020-238848</doi><oa>free_for_read</oa></addata></record> |
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subjects | Abscesses Antibiotics Breast cancer Breast Neoplasms - complications Breast Neoplasms - radiotherapy Cancer therapies Case Report Case reports Chronic illnesses Dermatology Dose Fractionation, Radiation Female Hidradenitis Suppurativa - complications Humans Mastectomy Medical imaging Metabolic syndrome Middle Aged Neoplasm Recurrence, Local - radiotherapy Pathogenesis Patients Radiation Dosage Radiation therapy Radiotherapy Radiotherapy - adverse effects Scars Sinuses Skin Skin - radiation effects Ulcers |
title | Delivery of high-dose radiation for recurrence of breast cancer in a patient with hidradenitis suppurativa |
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